Study of high - frequency electrocardiogram *

*The project is subsidized by National Nature Science Foundation of China.(39970205, 39270184, 3870613) **Address for correspondence: Jiguang Ge, Department of Biology, Zhejiang University, Hangzhou 310027, China. Telephone: (571) 5172242-3237. E-mail:[email protected] Abstract-High-frequency electrocardiogram (ECG) has been developed for more than 40 years and it is still not applied to clinic because there are some facts of causing high-frequency ECG (HFECG) and its mechanism are not understanding well, and the idiosyncrasy of patients appears not too clear formerly. We are interest in study of high-frequency information (HFI) in QRS complex and use animal model and some extraction methods to make sure its producing mechanism. The purpose of this article is to describe some good results which could explain some phenomena, that is high-frequency notching located on QRS complex is associated with myocardial injuries in which the small injury area exactly related with injecting formalin or ligaturing coronary artery. We also pointed that notching processing are necessary, and supplementary parameters should adopted, that the HFI has very useful value of idiosyncratic, local, early and dynamic characteristics for early diagnosis.